The evidence on injection of amniotic membrane for the treatment of plantar fasciitis includes preliminary
studies and a larger (n=145) patient-blinded comparison of micronized injectable-HAM and placebo
control. Injection of micronized amniotic membrane resulted in greater improvements in the visual analog
score for pain and the Foot Functional Index compared to placebo controls. The primary limitation of the
study is that this is an interim report with 12-month results pending. The evidence is insufficient to
determine the effects of the technology on health outcomes.